译文:
无菌生产流程中,最常用的截止阀是隔膜式截止阀,通常简称为隔膜阀。之所以在无菌生产流程中采用隔膜阀,一是因为它的结构简单,二是其价格便宜,这使得它到目前为止还几乎没有“竞争对手”。{wy}可以与隔膜阀竞争的是所谓的波纹管截止阀,即通常所说的波纹管阀。这种波纹管截止阀由于其价格太高,尽管有着比隔膜阀更好的技术上的优势,但是仍很难与隔膜阀进行抗衡,如本文所介绍的那样。
PTFE波纹管
在无菌流程工业领域中“波纹管阀与隔膜阀之间的竞争”由来已久。长期以来,隔膜阀以其结构简单,价格低廉和清洁xx方便而占据了优势。与隔膜阀相比,波纹管阀在市场上的品种规格太少。今天,Tuchenhagen生产的Vesta波纹管阀正是填补了这一空白,本文通过对隔膜阀与波纹管阀的比较,对两种阀的优缺点更加一目了然。
清空性能
当需要在水平管道中使用隔膜阀时,必须保证按照隔膜阀生产厂家规定的角度在水平管道中安装隔膜阀,否则在流程设备运行中,隔膜阀的清空会遇到一些问题,不能xx排出阀体中的介质。但是,不同的隔膜阀类型、不同厂家生产的隔膜阀、不同公称流量的隔膜阀的安装倾斜角度是不同的,又往往给无菌流程设备的设计制造带来了很xxx烦。在T型结构的隔膜阀中,这一清空阀体的问题表现得更加明显。
与隔膜阀相比,Vesta波纹管阀则不会出现这样的问题,无论Vesta波纹管阀的阀体是何种结构形式,在流程设备空载运行时都不会出现“死角”,从而保证严密地隔断管道。而且,它可按照不同的安装方式安装在无菌流程设备的管道系统中。
在医药制造业中,无菌流程设备由许多水平管道和垂直管道组成,在制药设备的设计中,由于管道位置和技术方面的原因,必须在特定的位置安装使用这种波纹管阀。例如,如果在垂直的管道中安装了隔膜阀,则须在同一水平面内经一个90°弯管的连接。而T型结构的隔膜阀的生产成本又很高,与不同阀体结构外形的隔膜阀相比,波纹管阀则在体积和外形上,与管道的连接安装更具优势。由于两类截止阀的结构类型不同,因此,在无菌流程设备设计的初期,就应选择好各个部位应选用哪种类型的截止阀。
在医药、食品和生物技术领域中的输出设备有着大量的需要xx的阀类。而大型的阀类,例如Stericom系列的,在这种需要xx的场合下几乎没有用武之地。因为,在这些流程设备中,要求输送的介质量越来越少,对于较少的流量,人们几乎无一例外地选择了隔膜阀。而新的波纹管阀有着较小的体积,可以与不同的管道直径配用,在这方面比隔膜阀更具优势。
设备利用率的比较
作为设备的使用者,在整个设备的使用周期内尽可能多地利用设备进行生产,也就是说:设备的利用率应尽可能的高。而设备的维护保养则表示设备必须得停止生产,而且还要投入一定的设备维护保养费用。波纹管阀一般都有磨损现象;在隔膜阀中,阀一旦出现磨损,经过一定的使用时间后必须更换隔膜,隔膜的使用寿命长短取决于相应的生产流程。一方面,流程设备中流通介质的腐蚀,管道清理和xx时的温度,流程设备的工作压力以及流量等工作参数会影响隔膜使用寿命;另一方面隔膜式的截止阀开、关时隔膜的变形也是决定隔膜使用寿命的重要因素。
带气动驱动装置的Vesta波纹管截止阀
大多数隔膜阀的损坏并不是因为生产过程中的使用,相反,是因为机械的挤压作用而损坏。虽然隔膜阀的隔膜有着不同的弹性等级、有不同涂层、和不同的PTFE护板,但是,对于所有的隔膜阀都有从外部看不见的磨损(由内部介质引起的表面腐蚀和微粒附着)。因此,为了避免无菌流程生产因隔膜阀的损坏而被迫停产,在实践中通常是在规定的使用寿命期前更换隔膜。这样一来,无论是强制更换的隔膜数量,还是由此而产生维修费用,或者设备的停机时间,都比PTFE波纹管阀明显要多,而波纹管阀的另一个优点是:几乎可用于各种流程生产过程。
核心部件 Vesta波纹管阀的关键部件是TFM1705
PTFE制造的截止波纹管,它除了可以抵抗各种化学介质的腐蚀之外,TFM1705材料还满足了FDAxx法规第21条§177.1550关于“全氟碳化物树脂”的要求。其光滑的表面(Ra≤0.8mm)、可靠的密封、较大的开关运动距离等这些特性特征,对于{zj0}的CIP/SIPxx清洁都是非常有利的。三年多来,这一获得专利技术的波纹管阀成功地在市场上站稳了脚跟,并且可以在无菌流程管道中严格地将管道内与管道外的大气环境隔绝开来。
“ aseptic diaphragm valves and process equipment, bellows valves in comparison ”是由提供的国际阀门新闻,译文仅供参考。另外,中国隔膜阀网还提供相关产品搜索:、、、、等。
原文:
Aseptic production process, the most commonly used cut-off valve is
a diaphragm-type globe valve, usually referred to as diaphragm
valves. The reason why the production process used in aseptic
diaphragm valves, both because of its simple structure, second, it
is cheap, which makes it so far is almost no "competitor." The only
way to compete with the diaphragm valves is the so-called bellows
globe valve, that is commonly referred to as bellows valves. This
bellows globe valve because of its price is too high, despite a better
technology than the advantages of diaphragm valves, but it is still
very difficult to compete with diaphragm valves, such as described
in this article. PTFE bellows In the sterile field of Process
Industry, "bellows the competition between the valve and diaphragm
valves," a long time. For a long time, diaphragm with its structure
is simple, inexpensive, and cleaning and disinfection take an
advantage of convenience. Compared with the diaphragm valves,
bellows valves in the market, too few varieties and specifications.
Today, Tuchenhagen production Vesta bellows valve is filled this
gap, this paper, the diaphragm valves with bellows valves compared
to the advantages and disadvantages of the two kinds of valve is
more clear. Empty Properties When you need to use the diaphragm
valves in horizontal piping, it must ensure that in accordance with
the provisions of the angle of Diaphragm Valves manufacturer to
install diaphragm valves in horizontal piping, or in the process
equipment operation, diaphragm of the empty encounter some
problems, can not be completely discharged valve in the media. However, different types
of diaphragm valves, different manufacturers of diaphragm valves,
diaphragm valves of different nominal flow of the installation of
tilt angle is different, often to the design and manufacture of
sterile process equipment has brought a lot of trouble. In the
T-type structure, diaphragm valves, this is showing clear the valve
of the more obvious. Compared with the diaphragm valves, Vesta
bellows valve is not such a problem, regardless of Vesta bellows
valve body what kind of structure, form, in the process equipment,
no-load run-time will not be a "dead", to ensure strict to cut off
pipeline. Moreover, it can be installed in different ways according
to aseptic process equipment installed in the piping system. In the
pharmaceutical manufacturing, aseptic process equipment by a number
of horizontal pipe and vertical pipe composition, in the
pharmaceutical equipment design, since the pipeline location and
technical reasons, must be installed in a specific location using
this bellows valves. For example, if a vertical pipe installed
diaphragm valves, must be in the same horizontal plane by an 90 °
elbow connection. The T-structure of the production cost and high
diaphragm valves, valve structures with different shape of the
diaphragm valves, compared bellows valves in size and appearance,
and installation of pipelines to connect an advantage. Because the
structure of two types of cut-off valves of different types, so in
the early stages of aseptic process equipment design, it should be
a good choice should be used in various parts of the type of
cut-off valve. In medicine, food and biotechnology in the output
device with a large number of valves required to be sterilized. The
large valve, for example, Stericom series, in which situations
required to be sterilized is almost useless. Because the equipment
in these processes require less and less the quality of delivery of
the IL, for less traffic, it is almost invariably chose the
diaphragm valves. The new bellows valve has a smaller size, can be
equipped with different pipe diameters used in this more
competitive than the diaphragm valves. Comparison of equipment
utilization As a device user, in the entire life cycle of the
device as much as possible the use of equipment for production,
that is: the utilization of equipment, as far as possible high.
Maintenance of the equipment, said equipment must have to stop
production, but also to invest certain amount of equipment
maintenance costs. Bellows valves generally have wear and tear; in
diaphragm valves, the valve once the wear and tear, after a certain
amount of time must be replaced using the diaphragm, diaphragm
depending on the life of the corresponding production process. On
the one hand, process equipment flow of media corrosion, pipeline
cleaning and disinfecting the temperature, process equipment, work
pressure and flow, and other operating parameters will affect the
membrane life; the other hand, diaphragm cut-off valve opening and
closing when the membrane deformation also decided to divide the
service life of important factors. With a pneumatic drive bellows
globe valve of the Vesta Diaphragm Valves not because of damage to
the majority of the production process used, on the contrary,
because of mechanical compression damage. Although the diaphragm
valves of the diaphragm have different levels of flexibility, there
are different coatings, and different PTFE shield, but for all of
the diaphragm valves
are invisible from the outside of the wear and tear (caused by
in-house media surface corrosion and particulate attachment) .
Therefore, in order to avoid the production of sterile process of
damage due to diaphragm valves forced to stop production, in
practice, is usually the life of a specified period before the
replacement of diaphragm. As a result, both the number of mandatory
replacement diaphragm, or the resulting maintenance costs, or
equipment downtime, than PTFE bellows valves is significantly more,
while the bellows valves Another advantage is: almost can be used
for the kinds of process production process. Core components Vesta
bellows valve manufacturing of key components is the deadline for
TFM1705 PTFE bellows, which in addition to corrosion resistance to
various chemical media, in addition, TFM1705 materials also meet
the FDA Code of Federal Regulations Article 21 of § 177.1550 on
"perfluorocarbons resin" requirements. Its smooth surface (Ra ≤
0.8mm), a reliable seal, the larger distance from the switching
movement characteristics of these features for optimal CIP / SIP
disinfection are very beneficial. More than three years, this
patented technology, bellows valves successful foothold in the
market, and aseptic processes in the pipeline will be strictly
outside the pipes and pipelines cut themselves off from the
atmospheric environment.
原文来源: