原文：
Department of Cardiothoracic Surgery, The University of Sydney, Royal Prince Alfred Hospital, Sydney, Australia b The Baird Institute for Applied Heart and Lung Surgical, Sydney, Australia c Department of Cardiology, The University of Sydney, Royal Prince Alfred Hospital, Sydney, Australia Received for publication May 21, 2009; revisions received June 28, 2009; accepted for publication August 9, 2009. * Address for reprints: Tristan D. Yan, BSc(Med), MBBS, PhD, The University of Sydney, Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney 2050, Australia. Objectives: The present systematic review objectively assessed the safety and clinical effectiveness of transcatheter aortic valve implantation for patients at high surgical risk with severe aortic stenosis. Methods: Electronic searches were performed in 6 databases from January 2000 to March 2009. The end points included feasibility, safety, efficacy, and durability. Clinical effectiveness was synthesized through a narrative review with full tabulation of results of all included studies. Results: The current evidence on transcatheter aortic valve implantation for aortic stenosis is limited to short-term observational studies. The overall procedural success rates ranged from 74% to {bfb}. The incidence of major adverse events included 30-day mortality (0%?25%), major ventricular tachyarrhythmia (0%?4%), myocardial infarction (0%?15%), cardiac tamponade (2%?10%), stroke (0%?10%), conversion to surgery (0%?8%), moderate to major paravalvular leak (4%?35%), vascular complication (8%?17%), valve-in-valve procedure (2%?12%), and aortic dissection/perforation (0%?4%). The overall 30-day major adverse cardiovascular and cerebral events ranged from 3% to 35%. The mean aortic valve area ranged from 0.5 to 0.8 cm2 before and 1.3 to 2.0 cm2 after transcatheter aortic valve implantation. The mean pressure gradient ranged from 34 to 58 mm Hg before and 3 to 12 mm Hg after transcatheter aortic valve implantation. There was no significant deterioration in echocardiography measurements during the assessment period. Death rate at 6 months postprocedure ranged from 18% to 48%. No studies had adequate follow-up to reliably evaluate long-term outcomes
原文来自：http://www.nytimes.com/1996/02/16/nyregion/new-jersey-daily-briefing-valve-caused-pipes-to-burst.html

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译文:阀门系统评价客观评估高风险手术的安全性
胸心外科，悉尼大学，皇家 阿尔弗雷德王子医院，悉尼，澳大利亚 b计算应用心脏和肺手术，悉尼，澳大利亚贝尔德研究所 丙部门的心脏，在悉尼大学，皇家阿尔弗雷德王子医院，悉尼，澳大利亚 接受出版2009年5月21日;修改收到2009年6月28日;接受出版2009年8月9日。 *联系地址重印：特里斯坦四严，理学士（医务），内外 全科医学士，博士，在悉尼，心胸外科，皇家阿尔弗雷德王子医院，2050年悉尼，澳大利亚系大学。 （电邮：Tristan.Yan @ unsw.edu.au）。 目标：本系统评价客观评估高风险手术的安全性和临床疗效的患者经导管主动脉瓣重度主动脉瓣狭窄植入。 方法：电子进行搜查，从2000年1月至2009年3月6数据库。该终点 包括可行性，安全性，有效性和持久性。临床疗效为原料，通过一个对所有纳入研究的结果充分说明审查汇总。 结果：目前的证据对经导管主动脉狭窄主动脉瓣植入xx于短期的观测研究。总的 手术成功率从74％至100％。主要不良事件的发生率，包括30天的死亡率（0％-25％），主要心室性心动过速（0％-4％），心肌梗死（0％-15％），心包填塞（2％-10％），中风（0％-10％），转为手术（0％-8％），中度主要瓣周漏（4％-35％），血管并发症（8％-17％），阀门在阀程序（ 2％-12％）和主动脉夹层/穿孔（0％-4％）。总的30天主要不良心血管 和脑血管事件介于3％至35％。主动脉瓣面积平均为0.50.8平方厘米之前和1.32.0平方厘米 导管后主动脉瓣植入术。平均压力梯度介于34至58毫米汞柱前3至12毫米汞柱后，经导管主动脉瓣植入术。有没有在超声心动图测量评价期间显着恶化。死亡术后的6个月不等率从18％到48％。没有研究有足够的后续可靠地评估长期结果

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