译文：
P-型ATP酶离子泵存在于几乎所有细胞膜中，推动离子逆其浓度梯度穿过细胞膜。结构研究在近年来取得巨大进展，现在我们对离子泵里面是什么样子已经知道了很多，但仍然不清楚它们是怎样在一侧收集离子而在另一侧释放它们。现在，通过利用海洋毒素palytoxin来解耦Na+、K+-ATP酶的泵离子转位通道的控制门，从而将该泵转变成一种阳离子通道，Nicolás Reyes 和 David Gadsby获得了关于离子泵作用方式的一个新观点。在细胞外侧，离子通道以一个又深、又宽的门廊的形式开始，这个门廊突然变窄，形成一个阳离子选择性过滤器，由酸性侧链组成。引人注目的是，将它们当中仅仅一个的负电荷逆转，就会将该通道从阳离子选择性通道变成阴离子选择性通道。

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原文：
P-type ion pump ATP enzyme present in almost all cell membranes and promote reverse its concentration gradient across the plasma membrane. Structure made great progress in recent years, and now we are inside the ion pump is what kind of already know a lot, but it remains unclear how they collected ions on one side while the other side of the release of them. Now, through the use of the marine toxin palytoxin to decoupling of Na +, K +-ATP enzyme pump ion translocation channel control gate, by which the pump into a cation channel, Nicolás Reyes, and David Gadsby received on the mode of action of an ion pump a new perspective. Outside the cell, ion channels with a deep, but also a wide porch in the form of the beginning, this porch suddenly narrows to form a cation-selectivity filter formed by the acidic side chain. Remarkably, among them only a reversal of the negative charge would be the passage from the cation-selective channel becomes anion-selective channel.