译文:
一、总述:
无菌生产流程中,最常用的截止阀是隔膜式截止阀,通常简称为隔膜阀。之所以在无菌生产流程中采用隔膜阀,一是因为它的结构简单,二是其价格便宜,这使得它到目前为止还几乎没有“竞争对手”。{wy}可以与隔膜阀竞争的是所谓的波纹管截止阀,即通常所说的波纹管阀。这种波纹管截止阀由于其价格太高,尽管有着比隔膜阀更好的技术上的优势,但是仍很难与隔膜阀进行抗衡。本文通过对隔膜阀与波纹管阀的比较,对两种阀的优缺点更加一目了然。
二、与隔膜阀比较,Vesta波纹管阀的优势:
在无菌流程工业领域中“波纹管阀与隔膜阀之间的竞争”由来已久。长期以来,隔膜阀以其结构简单,价格低廉和清洁xx方便而占据了优势。与隔膜阀相比,波纹管阀在市场上的品种规格太少。但是今天,uchenhagen生产的Vesta波纹管阀正是填补了这一空白。
(一)、Vesta波纹管阀性能优越的表现在以下方面: 1、清空性能
(1)、当需要在水平管道中使用隔膜阀时,必须保证按照隔膜阀生产厂家规定的角度在水平管道中安装隔膜阀,否则在流程设备运行中,隔膜阀的清空会遇到一些问题,不能xx排出阀体中的介质。但是,不同的隔膜阀类型、不同厂家生产的隔膜阀、不同公称流量的隔膜阀的安装倾斜角度是不同的,又往往给无菌流程设备的设计制造带来了很xxx烦。在T型结构的隔膜阀中,这一清空阀体的问题表现得更加明显。与隔膜阀相比,Vesta波纹管阀则不会出现这样的问题,无论Vesta波纹管阀的阀体是何种结构形式,在流程设备空载运行时都不会出现“死角”,从而保证严密地隔断管道。而且,它可按照不同的安装方式安装在无菌流程设备的管道系统中。
2、在医药制造业中,无菌流程设备由许多水平管道和垂直管道组成,在制药设备的设计中,由于管道位置和技术方面的原因,必须在特定的位置安装使用这种波纹管阀。例如,如果在垂直的管道中安装了隔膜阀,则须在同一水平面内经一个90°弯管的连接。而T型结构的隔膜阀的生产成本又很高,与不同阀体结构外形的隔膜阀相比,波纹管阀则在体积和外形上,与管道的连接安装更具优势。由于两类截止阀的结构类型不同,因此,在无菌流程设备设计的初期,就应选择好各个部位应选用哪种类型的截止阀。
3、在医药、食品和生物技术领域中的输出设备有着大量的需要xx的阀类。而大型的阀类,例如Stericom系列的,在这种需要xx的场合下几乎没有用武之地。因为,在这些流程设备中,要求输送的介质量越来越少,对于较少的流量,人们几乎无一例外地选择了隔膜阀。而新的波纹管阀有着较小的体积,可以与不同的管道直径配用,在这方面比隔膜阀更具优势。
2、核心部件 Vesta波纹管阀的关键部件是TFM1705
PTFE制造的截止波纹管,它除了可以抵抗各种化学介质的腐蚀之外,TFM1705材料还满足了FDAxx法规第21条§177.1550关于“全氟碳化物树脂”的要求。其光滑的表面(Ra≤0.8mm)、可靠的密封、较大的开关运动距离等这些特性特征,对于{zj0}的CIP/SIPxx清洁都是非常有利的。三年多来,这一获得专利技术的波纹管阀成功地在市场上站稳了脚跟,并且可以在无菌流程管道中严格地将管道内与管道外的大气环境隔绝开来。
3、设备利用率的比较
作为设备的使用者,在整个设备的使用周期内尽可能多地利用设备进行生产,也就是说:设备的利用率应尽可能的高。而设备的维护保养则表示设备必须得停止生产,而且还要投入一定的设备维护保养费用。波纹管阀一般都有磨损现象;在隔膜阀中,阀一旦出现磨损,经过一定的使用时间后必须更换隔膜,隔膜的使用寿命长短取决于相应的生产流程。一方面,流程设备中流通介质的腐蚀,管道清理和xx时的温度,流程设备的工作压力以及流量等工作参数会影响隔膜使用寿命;另一方面隔膜式的截止阀开、关时隔膜的变形也是决定隔膜使用寿命的重要因素。大多数隔膜阀的损坏并不是因为生产过程中的使用,相反,是因为机械的挤压作用而损坏。虽然隔膜阀的隔膜有着不同的弹性等级、有不同涂层、和不同的PTFE护板,但是,对于所有的隔膜阀都有从外部看不见的磨损(由内部介质引起的表面腐蚀和微粒附着)。因此,为了避免无菌流程生产因隔膜阀的损坏而被迫停产,在实践中通常是在规定的使用寿命期前更换隔膜。这样一来,无论是强制更换的隔膜数量,还是由此而产生维修费用,或者设备的停机时间,都比PTFE波纹管阀明显要多,因此波纹管阀性能好耐用,使用寿命更长。带气动驱动装置的Vesta波纹管截止阀的另一个优点是:几乎可用于各种流程生产过程。
“ Vesta sterile production facilities in the advantages of bellows valves”是由提供的国际阀门新闻,译文仅供参考。另外,中国隔膜阀网还提供相关产品搜索:、、、、等。
原文:
I. Overview: Aseptic production process, the most commonly used
cut-off valves are diaphragm-type globe valve, usually referred to
as Diaphragm Valves. The reason why the production process used in
aseptic diaphragm valves, both because of its simple structure and
second, it is cheap, which makes it so far is almost no
"competitor." The only way to compete with the diaphragm valves is
the so-called bellows globe valve, that is commonly referred to as
bellows valves. This bellows globe valve
because of its price is too high, despite a better technology than
the advantages of diaphragm valves, but it is still very difficult
to compete with diaphragm valves. This article, through diaphragm
valves with bellows valves compared to the advantages and
disadvantages of the two valves is more clear. Second, compared
with the diaphragm valves, Vesta bellows valves advantages: In the
sterile field of Process Industry, "bellows the competition between
the valve and diaphragm valves," a long time. For a long time,
diaphragm with its structure is simple, inexpensive, and cleaning
and disinfection take an advantage of convenience. Compared with
the diaphragm valves, bellows valves in the market, too few
varieties and specifications. But today, uchenhagen production
Vesta bellows valve is filled this gap. (A), Vesta bellows valves
superior performance in the following areas: 1, clear performance
(1), when required in the horizontal pipe when the use of diaphragm
valves, diaphragm valves must be guaranteed in accordance with the
provisions of the perspective of the manufacturer to install
diaphragm valves in horizontal piping, or in process equipment
operation, diaphragm valves of the empty will encounter some
problems, can not fully discharge valve in the media. However,
different diaphragm valves types, different manufacturers of
diaphragm valves, diaphragm valves of different nominal flow
installation of tilt angle is different, often to the design and
manufacture of sterile process equipment has brought a lot of
trouble. In the T-type structure, diaphragm valves, this is showing
clear the valve of the more obvious. Compared with the diaphragm
valves, Vesta bellows valve is not such a problem, regardless of
Vesta Body bellows valves what kind of structural form, in the
process equipment, no-load run-time will not be a "dead", to ensure
strict to cut off pipeline. Moreover, it can be installed according
to different methods of equipment installed in the sterile process
piping systems. 2, in the pharmaceutical manufacturing industry,
the aseptic process equipment by a number of horizontal pipe and
vertical pipe composition, in the pharmaceutical equipment design,
since the pipeline location and technical reasons, must be
installed in a specific location using this bellows valves . For
example, if a vertical pipe installed diaphragm valves, must be in
the same horizontal plane by an 90 ° elbow connection. The
T-structure of the production cost and high diaphragm valves, valve
structures with different shape of the diaphragm valves, compared
bellows valves in the size and appearance, and installation of
pipelines to connect an advantage. Because the structure of two
types of cut-off valves of different types, so in the early stages
of aseptic process equipment design, it should be a good option
should be used in various parts of the type of cut-off valves. 3,
in medicine, food and biotechnology in the field of the output
device with the need for a large number of sterile valve. And the
large valve, for example, Stericom series, in which situations
required to be sterilized is almost useless. Because the equipment
in these processes require less and less the quality of delivery of
the IL, for less traffic, it is almost invariably chosen diaphragm
valves. The new bellows valve has a smaller volume, can be equipped
with different pipe diameters used in this more competitive than
the diaphragm valves. 2, the core components Vesta bellows valves
manufactured key components is the deadline for TFM1705 PTFE
bellows, which in addition to corrosion resistance to various
chemical media, in addition, TFM1705 materials also meet the FDA
Code of Federal Regulations Article 21 of § 177.1550 on the
"perfluoro carbide resin "requirements. Its smooth surface (Ra ≤
0.8mm), a reliable seal, the larger distance from the switching
movement characteristics of these features for optimal CIP / SIP
disinfection are very beneficial. More than three years, this
patented technology, bellows valves successful foothold on the
market, and aseptic processes in the pipeline will be strictly
outside the pipes and pipelines cut themselves off from the
atmospheric environment. 3 Comparison of capacity utilization As a
device user, in the entire life cycle of the device as much as
possible the use of equipment for production, that is: the
utilization of equipment, as far as possible high. Maintenance of
the equipment, said equipment must have to stop production, but
also to invest certain amount of equipment maintenance costs.
Bellows valves generally have wear and tear; in diaphragm valves,
the valve once the wear and tear, after a certain amount of time
must be replaced using the diaphragm, diaphragm depending on the
life of the corresponding production process. On the one hand,
process equipment flow of media corrosion, pipeline cleaning and
disinfection when the temperature, pressure and process
equipment, work flow, and other operating parameters will affect
the membrane life; the other hand, diaphragm cut-off valve opening
and closing when the membrane deformation also decided to divide
the service life of important factors. Most of the diaphragm valves
is not because of damage to the use of the production process, on
the contrary, because mechanical compression damage. Although the
diaphragm valves of the diaphragm have different levels of
flexibility, there are different coatings, and different PTFE
shield, but for all of the diaphragm valves are invisible from the
outside of the wear and tear (caused by in-house media surface
corrosion and particulate attachment) . Therefore, in order to
avoid the sterile production process of damage due to diaphragm
valves forced to stop production, in practice, is usually a
specified period before the replacement of diaphragm life. As a
result, both the number of mandatory replacement of membrane, or
maintenance costs arising therefrom, or equipment downtime, than
PTFE bellows valves is significantly more, so good performance
bellows valve durability, long life. With a pneumatic drive bellows
globe valve of Vesta Another advantage is: Almost all kinds of
processes can be used for the production process.
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