译文：
光控的蛋白质通道也许代表了一种新一代的纳米技术工具。 　　从理论上讲，建造一个纳米设备并非xx不同于建造其它的设备，工程师{dy}步设计出必需的部件，然后再决定如何将它们组装起来实现既定功能。然而，建造纳米设备的{zd0}困难是必须在这个尺度内进行有效的设计。幸运的是，进化成功地解决了无数的工程挑战，科学家在蛋白质的世界里总能发现给人灵感的自然设计。 　　荷兰哥尼根大学和BiOMaDe技术中心的研究人员展示了这种方法的力量。Ben Feringa解释说，MscL是大肠杆菌上的一种膜蛋白，它属于控制物质进出细胞的管道，在光的作用下它会可逆转地开或关，在自然的系统里，这就是一种安全阀。他说：“它能防止细胞爆裂，如果细胞内的压力过大，通道的小孔就会张开3个纳米，许多东西就会流出去。因此，它是一个非常好的通道，能自动张开的、理想的状态能控制它的开和关。” 　　通常情况下，MscL因疏水作用总是紧闭的。但是，如果有相当的负荷，MscL的小孔就会被迫一直张开，直到负荷消失。Feringa和同事设计了一种可逆转的光开关，在紫外光的作用下会充电，而在可见光的作用下会放电。这种开关附着在MscL单体的特殊部位，经过改造的蛋白质被送进合成膜。实验确证，紫外光能诱导通道的张开，直至在可见光的作用下重新合上。在第二轮的实验中，研究人员将经过改造的MscL注入微脂质体内，脂质体内含有荧光染剂，实验显示，除了少量的泄漏以外，光能有效地调节脂质体内的荧光染剂的释放。 　　这只是一个最初的发现，研究人员们正在改进这种方法，他们希望这种技术能应用于可控的xx输送上。Feringa有更远大的目标，他预见了这些微型设备的巨大功能，并相信它们能够成为精密纳米设备的基本构件。他说：“在纳米技术领域，我们很少知道如何整合零件、如何组装它们并让它们恰当地工作。”“当基本原理被证明后，新的挑战就是看看如何将这种纳米阀与部分纳米流体通道结合起来，行使阀门的功能。”

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原文：
Light control of protein channels may represent a new generation of nano-technology tools. In theory, the construction of a nano-device is not completely different from the construction of other devices, engineers designed the first step necessary components, and then decide how they are assembled together to accomplish intended function. However, the construction of nano-equipment, the greatest difficulty is the need to carry out effective this scale design. Fortunately, evolution has successfully solved numerous engineering challenges, scientists in the protein world always gives the inspiration found in the natural design. Helangeni University of Michigan and BiOMaDe Technology Center researchers have demonstrated the power of this approach. Ben Feringa explained, MscL is a kind of E. coli membrane proteins, which are controlled substances out of cells in the pipeline, in the light it will be reversed under way on or off, in a natural system, this is a safe valve. He said: "It can prevent the cells burst, if excessive pressure inside the cell, the channel will be open hole 3 nm, many things begin to go out. Thus, it is a very good channel, can automatically Zhang opened, the ideal state to control its on and off. " Under normal circumstances, MscL is always closed due to hydrophobic interactions of. However, if there is a considerable load, MscL hole will be forced to remain open until the load disappears. Feringa and his colleagues designed a reversible optical switch, under the influence of ultraviolet light will be charged, while under the influence of visible light would be discharged. This switch attached to the MscL monomer special parts were sent through the transformation of the protein synthetic membranes. Experiments confirm, UV-induced channel open, until the role of visible light on the re-combined. In the second round of experiments, the researchers will go through a transformation of the MscL in vivo injection of micro-lipid, lipid bodies contain fluorescent dye, experiments showed that, in addition to a small amount of leakage outside the light energy to effectively regulate body lipid fluorescent dye release. This is just an initial discovery, researchers are working to improve this approach, they hope this technology can be used in the controlled drug delivery. Feringa a broader vision, he foresaw the great features of these micro-devices, and believe they can become an essential component of sophisticated nano-devices. He said: "In the nanotechnology area, we rarely know how to integrate parts, how to assemble them and make them work properly." "When the basic principles have been proven, the new challenge is to see how the valve and part of such nano - combination of nano-fluid channels, the exercise of the valve function. "